Methods to compare the dissolution profile
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Oct 23, 2022
4.There are several methods to compare the dissolution profile. Details are summarized in given as follows: 1. Visual process of comparison (Graphs) 2. Statistical analysis -t-test -Analysis-of-variance (ANOVA) 3. Model-dependent-methods -Zero order -First order -Hixson Crowell cube root law -Takeru Higuchi model -Weibull model -Korsemeyar and peppas model 4. Model-independent-methods -Ratio Test Procedure -Pair Wise Procedure/ Difference factor (f1) and Similarity factor (f2) -Multivariate Confidence Regi0n Procedure