Most common 14 tablet defects at coating stage
Download Free High-Resolution Poster of Tablet Defects – refer to the end section of this article.
Tablet defects at coating stage can occur because of various reasons, which can be easily prevented from occurrence. To eliminate the possibility of the defects, the process of tablet coating should be fully understood by the manufacturer.
Adequate scientific and academic knowledge along with hands-on training of tablet coating, setting of the machine, and continuous monitoring plays a vital role in manufacturing high-quality tablets.
The technician should have adequate knowledge about the setting of the machine, trouble shooting, and the skill to operate the machine to manufacture high-quality products.
What are the common tablet defects at coating stage?
There are following commonly observed Tablet-Defects:
(04) Sticking or Picking
(08) Color Variation
(10) Orange Peel or Roughness
(11) Cracking or Splitting
To get FREE High Resolution Tablet Defects Poster, refer end section of the page.
Blistering means blistering of a surface film appears when film becomes detached from the tablet’s substrate.
Chipping means dented and chipped film mostly on the edges of the tablet.
Cratering means volcanic like cratering happens exposing the tablet surface.
Sticking or Picking
Sticking or picking means sticking of film with each other or with the coating pan resulting to some of the tablet pieces being detached from the core.
Pitting is the deformation of the core of the tablet without any visible signs of disruption of the film coating.
Blooming is the fading or dulling of a tablet color after when it is stored for prolonged period at a high temperature.
Blushing is described as appearance of white specks or a haziness in the film.
Color variation of tablet film.
This refers to the filling of intagliations – i.e., the distinctive words or symbols formed on the tablet.
Orange Peel or Roughness
When film having a rough surface or have a matt surface rather than glossy texture. It appear same as an orange.
Cracking or Splitting
The cracking defect observes when the film coating of the tablet cracks in the crown area or splits around the edges.
Twinning is when two tablets sticks together.
Coating gets removed from the surface due to friction between tablets.
When coating material fills in the the logo or letter, bridging occurs.