July 20, 2021: Pharmaceutical Interview Questions and Answers

#MicronRatingOfFingerBags, #CalculatingFriabilityTest, #LimitOfFriability, #Rheology, #TypesOfExcipients

1. What are the typically seen micron rating of Finger Bags used for Fluid Bed Dryer (FBD) or Fluid Bed Processor (FBP)?

Micron Rating: 1, 5, 10, 15, 25, 50, 100

2. What is the formula for calculating friability test results?

Friability (%) = Weight 1 – Weight 2 / Weight 1 X 100

Where,

Weight 1 = Weight of Tablets (Initial / Before Tumbling) & Weight 2 = Weight of Tablets (After Tumbling or friability)

3. What is the limit of friability test results?

Limit: Friability (%) = Not More Than 1.0 %

4. What is Rheology?

Rheology (Greek words rheos meaning flow and logos meaning science) is the study of the flow under the influence of stress. The principle can be applied to solids, liquids, and gases.

5. Explain the types of excipients.

Organoleptic
o Color
o Flavor
o Sweetener
Stabilizers
o Preservative
o Antioxidant
o Emulsifier
o Suspending Agent
Dose Accuracy
o Diluent
o Bulking agent
o Filler
Process Aids
o Binder
o Lubricant
o Glidant
o Anti-adherent
Drug release
o Disintigrant
o Penetration enhancer
o Coating agent

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